FtsZ-IN-1
Product Specifications
UNSPSC Description
FtsZ-IN-1 is a potent FtsZ inhibitor with quinolinium ring. FtsZ-IN-1 has stronger antibacterial activity against Gram-positive bacteria with MICs of 0.5-8 μg/mL. FtsZ-IN-1 significantly causes cell elongation of B. subtilis by enhancing FtsZ polymerization. FtsZ-IN-1 exhibits low hemolytic toxicity and low tendency to induce agent resistance. FtsZ-IN-1 has against drug-resistant bacteria activity[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ftsz-in-1.html
Solubility
10 mM in DMSO
Smiles
CC1CCN(C2=C3C=CC=CC3=[N+](C)C(/C=C/C4=CC=C(N(C)C)C=C4)=C2)CC1.[I-]
Molecular Weight
513.46
References & Citations
[1]Zhong DX, She MT, Guo XC, et al. Design and synthesis of quinolinium-based derivatives targeting FtsZ for antibacterial evaluation and mechanistic study. Eur J Med Chem. 2022;236:114360.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146595/FtsZ-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146595/
Clinical Information
No Development Reported
CAS Number
2516246-24-3
Curated Selection
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