Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Keap1-Nrf2-IN-7

Keap1-Nrf2-IN-7 (compound 7v) is a potent Keap1-Nrf2 PPI (Keap1-Nrf2 protein−protein interaction) inhibitor with an IC50 of 0.45 µM[1].

Product Specifications

CAS Number

[2769963-42-8]

UNSPSC

12352005

Target

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/keap1-nrf2-in-7.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C=C1)S(=O)(N(C2=CC=C(C(OCC3=CC=C(C=C3)F)=C2)N(S(=O)(C4=CC=C(C=C4)C)=O)CC(O)=O)CC(O)=O)=O

Molecular Formula

C31H29FN2O9S2

Molecular Weight

656.70

References & Citations

[1]Lee S, et al. Structure-activity relationships of 1,4-bis (arylsulfonamido) -benzene or naphthalene-N, N'-diacetic acids with varying C2-substituents as inhibitors of Keap1-Nrf2 protein-protein interaction. Eur J Med Chem. 2022 Jul 5;237:114380.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ACSM4 Human Gene Knockout Kit (CRISPR)
KN413310 1 Kit

ACSM4 Human Gene Knockout Kit (CRISPR)

Ask
View Details
Anti-RNF222 Antibody
CTA4616-01 30 µL

Anti-RNF222 Antibody

Ask
View Details
Anti-RNF222 Antibody
CTA4616-02 50 μL

Anti-RNF222 Antibody

Ask
View Details
Anti-RNF222 Antibody
CTA4616-03 100 µL

Anti-RNF222 Antibody

Ask
View Details
Anti-RNF222 Antibody
CTA4616-04 200 µL

Anti-RNF222 Antibody

Ask
View Details
MYEOV, ID (MYEOV, OCIM, Myeloma-overexpressed gene protein, Oncogene in multiple myeloma) (PE) discontinued
038727-PE 200 µL

MYEOV, ID (MYEOV, OCIM, Myeloma-overexpressed gene protein, Oncogene in multiple myeloma) (PE) discontinued

Ask
View Details