Xanthine oxidase-IN-6
Xanthine oxidase-IN-6 (Compound 6c) is a potent, orally active, mixed-type xanthine oxidase (XOD) inhibitor with an IC50 value of 1.37 μM. Xanthine oxidase-IN-6 shows strong anti-hyperuricemia and renal protective activity[1].
Product Specifications
UNSPSC
12352005
Target
NF-κB; TNF Receptor; Toll-like Receptor (TLR) ; Xanthine Oxidase
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidase-in-6.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12CC=C([C@]1(C(OC=C2C(NC3=NC=CO3)=O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4OC(C)=O)OC(C)=O)OC(C)=O)COC(C)=O)[H])COC(C)=O
Molecular Formula
C29H34N2O15
Molecular Weight
650.58
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NF-κB; TLR4; TNFRSF5/CD40
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