Xanthine oxidase-IN-6
Product Specifications
UNSPSC Description
Xanthine oxidase-IN-6 (Compound 6c) is a potent, orally active, mixed-type xanthine oxidase (XOD) inhibitor with an IC50 value of 1.37 μM. Xanthine oxidase-IN-6 shows strong anti-hyperuricemia and renal protective activity[1].
Target Antigen
NF-κB; TNF Receptor; Toll-like Receptor (TLR); Xanthine Oxidase
Type
Reference compound
Related Pathways
Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidase-in-6.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12CC=C([C@]1(C(OC=C2C(NC3=NC=CO3)=O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4OC(C)=O)OC(C)=O)OC(C)=O)COC(C)=O)[H])COC(C)=O
Molecular Weight
650.58
References & Citations
[1]Jia-shu Chen, et al. Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis. Eur J Med Chem. 2022 Apr 20;237:114379.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146560/Xanthine-oxidase-IN-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146560/
Clinical Information
No Development Reported
Curated Selection
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