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Antitubercular agent-16

Antitubercular agent-16 (Compound 5q) is an antitubercular agent with MIC90 values of 0.40, 20.11, 23.51, 19.62, 10.93 and 13.62 μg/mL against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161, respectively. Antitubercular agent-16 shows low cytotoxicity against macrophages and pulmonary fibroblasts[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antitubercular-agent-16.html

Solubility

10 mM in DMSO

Smiles

CC1=CC(CNCC2CCCCC2)=C(N1C3=NC4=C(S3)C=CC=C4)C

Molecular Formula

C21H27N3S

Molecular Weight

353.52

References & Citations

[1]Semenya D, et al. Tapping into the antitubercular potential of 2,5-dimethylpyrroles: A structure-activity relationship interrogation. Eur J Med Chem. 2022 Jul 5;237:114404.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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