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Antitubercular agent-15

Antitubercular agent-15 (Compound 5n) is an antitubercular agent with MIC90 values of 0.73, 7.69, 9.38, 18.80, 7.53 and 7.31 μg/mL against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161, respectively. Antitubercular agent-15 shows low cytotoxicity against macrophages and pulmonary fibroblasts[1].

Product Specifications

CAS Number

9007-83-4

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antitubercular-agent-15.html

Solubility

10 mM in DMSO

Smiles

CC1=CC(CNCC2CCCCC2)=C(N1CC3=CC=C(C=C3)F)C

Molecular Formula

C21H29FN2

Molecular Weight

328.47

References & Citations

[1]Semenya D, et al. Tapping into the antitubercular potential of 2,5-dimethylpyrroles: A structure-activity relationship interrogation. Eur J Med Chem. 2022 Jul 5;237:114404.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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