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C-ABL-IN-4

C-ABL-IN-4 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-4 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 54) [1].

Product Specifications

CAS Number

2626934-68-5

UNSPSC

12352005

Target

Bcr-Abl

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/c-abl-in-4.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN(C(C=C1)=O)C2=CN=CC(F)=C2)NC3=CC=C(C=C3)OC(F)(Cl)F

Molecular Formula

C18H11ClF3N3O3

Molecular Weight

409.75

References & Citations

[1] Michael J. RAWLING, et al. New compounds and methods. Patent WO2021048567A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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