C-ABL-IN-3
C-ABL-IN-3 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-3 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) and cancer (extracted from patent WO2021048567A1, compound 50) [1].
Product Specifications
CAS Number
2626934-64-1
UNSPSC
12352005
Target
Bcr-Abl
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/c-abl-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C(C=C1)=CN(C2=CN=CN=C2)C1=O)NC3=CC=C(OC(F)(F)F)C=C3
Molecular Formula
C17H11F3N4O3
Molecular Weight
376.29
References & Citations
[1]Michael J. RAWLING, et al. New compounds and methods. Patent WO2021048567A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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