TRK-IN-17
TRK-IN-17 is a potent inhibitor of TRK. Tropomyosin-related kinases (Trks) are a family of receptor tyrosine kinases activated by neurotrophins, a group of soluble growth factors including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Neurotrophin-3 (NT-3) and Neurotrophin-4/5 (NT-4/5) . TRK-IN-17 has the potential for the research of cancer diseases (extracted from patent WO2021148807A1, compound 3) [1].
Product Specifications
CAS Number
2409544-80-3
UNSPSC
12352005
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trk-in-17.html
Solubility
10 mM in DMSO
Smiles
CCN/C(C1=CN=C2C=CC(N3C[C@H](C[C@@H]3C4=CC(F)=CC(SC)=C4)F)=NN12)=N\C#N
Molecular Formula
C21H21F2N7S
Molecular Weight
441.50
References & Citations
[1]Nicola ROBAS, et al. Pharmaceutical compositions and their uses. Patent WO2021148807A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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