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TRK-IN-16

TRK-IN-16 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-16 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-21) [1].

Product Specifications

CAS Number

1365212-81-2

UNSPSC

12352005

Target

Trk Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/trk-in-16.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CN=C2C=CC(N3CCCC3C4=CC(F)=CC=C4)=NN21)NCC

Molecular Formula

C19H20FN5O

Molecular Weight

353.39

References & Citations

[1]Yi Fan, et al. Imidazo [1, 2] pyridazin compounds and compositions as trk inhibitors. Patent WO2012034091A1.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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