TRK-IN-14
TRK-IN-14 is a potent inhibitor of TRK. Protein kinases play a critical role in the control of cell growth and differentiation and are responsible for the control of a wide variety of cellular signal transduction processes. TRK-IN-14 has the potential for the research of TRK-related diseases (extracted from patent WO2012034091A1, compound X-47) [1].
Product Specifications
CAS Number
1365212-84-5
UNSPSC
12352005
Target
Trk Receptor
Type
Reference compound
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/trk-in-14.html
Solubility
10 mM in DMSO
Smiles
FC(C=C1)=CC=C1CNC(C2=CN=C3N2N=C(N4[C@](C5=CC(F)=CC=C5)([H])CCC4)C=C3)=O
Molecular Formula
C24H21F2N5O
Molecular Weight
433.45
References & Citations
[1]Yi Fan, et al. Imidazo [1, 2] pyridazin compounds and compositions as trk inhibitors. Patent WO2012034091A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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