isoCA-4
Product Specifications
UNSPSC Description
isoCA-4, a Combretastatin A4 derivative, is a tubulin polymerization inhibitor. isoCA-4 has anti-proliferative activities[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/isoca-4.html
Solubility
10 mM in DMSO
Smiles
C=C(C1=CC(OC)=C(C(OC)=C1)OC)C2=CC(O)=C(C=C2)OC
Molecular Weight
316.35
References & Citations
[1]Xiang-Yu Yan, et al. Design, synthesis, and biological evaluation of novel diphenylamine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site. Eur J Med Chem. 2022 Apr 16;237:114372.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146506/isoCA-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146506/
Clinical Information
No Development Reported
CAS Number
1067880-31-2
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