Tubulin polymerization-IN-6
Tubulin polymerization-IN-6 (compound 5f) is a potent tubulin polymerization inhibitor, with an IC50 of 1.09 μM. Tubulin polymerization-IN-6 inhibits cell migration and tube formation and contributes to the anti-angiogenesis. Tubulin polymerization-IN-6 can greatly inhibit tumor growth on HT29 xenograft Balb/c nude mice[1].
Product Specifications
CAS Number
2768613-52-9
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-6.html
Solubility
10 mM in DMSO
Smiles
COC(C1=CC2=C(OCCO2)C=C1NC3=CC(OC)=C(C(OC)=C3)OC)=O
Molecular Formula
C19H21NO7
Molecular Weight
375.37
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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