Topoisomerase I/II inhibitor 3
Selected Variant
HY-146504
Size: 1 Each
Topoisomerase I/II inhibitor 3 (compound 7) is a potent topoisomerase I (Topo I) and II (Topo II) dual inhibitor. Topoisomerase I/II inhibitor 3 can inhibit cell proliferation, invasion and migration, and induce apoptosis by inhibiting PI3K/Akt/mTOR signaling pathway. Topoisomerase I/II inhibitor 3 can be used for liver cancer research[1].
Product Specifications
CAS Number
2770804-74-3
UNSPSC
12352005
Target
Apoptosis; PI3K; Reactive Oxygen Species (ROS) ; Topoisomerase
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-ii-inhibitor-3.html
Solubility
10 mM in DMSO
Smiles
C1(C=CC2=C3C=NC(C4=CC5=C(OCO5)C=C4CN6CCCCCC6)=C2)=C3OCO1
Molecular Formula
C24H24N2O4
Molecular Weight
404.46
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PI3K; Topo I; Topo II
Price
Frequently Asked Questions
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