Topoisomerase I inhibitor 7
Selected Variant
HY-146497
Size: 1 Each
Topoisomerase I inhibitor 7 (Compound 8) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 7 significantly inhibits tumor growth (up to 79%) and increases the lifespan (153%) of mice bearing P388 lymphoma transplants. Topoisomerase I inhibitor 7 indicates prospects for further search of new antitumor agent candidates among the heteroarene-fused anthraquinones[1].
Product Specifications
CAS Number
2408639-81-4
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-inhibitor-7.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=C(C3=C(C(O)=C2N1)C(C4=C(C3=O)C=CC=C4)=O)O)C(N5CC[C@@H](C5)N)=O
Molecular Formula
C22H19N3O5
Molecular Weight
405.40
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
Frequently Asked Questions
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