PPARγ agonist 6

PPARγ agonist 6 (Compound 12) is a potent and selective agonist of PPARγ. PPARγ agonist 6 has the potential for the research of cancer diseases[1].

Product Specifications

CAS Number

2428742-08-7

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/pparγ-agonist-6.html

Solubility

10 mM in DMSO

Smiles

CCCC1=NC2=C(C=CC=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C(OC)=O)C(OC)=O

Molecular Formula

C27H26N2O4

Molecular Weight

442.51

References & Citations

[1]Schoepf AM, et al. Identification and development of non-cytotoxic cell death modulators: Impact of sartans and derivatives on PPARγ activation and on growth of imatinib-resistant chronic myelogenous leukemia cells. Eur J Med Chem. 2020 Jun 1;195:112258.