A3AR antagonist 1
Product Specifications
UNSPSC Description
A3AR antagonist 1 (compound 17) is a potent and selective human A3 adenosine receptor (AR) antagonist, with an Ki of 4.63 nM. A3AR antagonist 1 shows no affinity for the rat A3 AR even at high concentrations[1].
Target Antigen
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a3ar-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)C(NC2=NC(C3=CC=CC=C3)=C(S2)C4=NC5=C(C(N4C6=CC=C(C=C6)OC)=O)C=CC=C5)=O
Molecular Weight
560.62
References & Citations
[1]Abdelrahman A, et, al. Substituted 4-phenylthiazoles: Development of potent and selective A 1, A 3 and dual A 1/A 3 adenosine receptor antagonists. Eur J Med Chem. 2020 Jan 15;186:111879.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146457/A3AR-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146457/
Clinical Information
No Development Reported
CAS Number
2413257-74-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1202894 Inquire
Recombinant Xenopus laevis RDS/peripherin-like protein xRDS36 (rds36)
Ask
View Details MBS6356102-01 0.1 mL
TM9SF2, NT (TM9SF2, Transmembrane 9 superfamily member 2, p76) (MaxLight 405)
Ask
View Details MBS6356102-02 5x 0.1 mL
TM9SF2, NT (TM9SF2, Transmembrane 9 superfamily member 2, p76) (MaxLight 405)
Ask
View Details 
MBS097929-01 48 Well
Mouse Neuroblastoma, Suppression of Tumorigenicity 1 ELISA Kit
Ask
View Details MBS097929-02 96 Well
Mouse Neuroblastoma, Suppression of Tumorigenicity 1 ELISA Kit
Ask
View Details