Antiproliferative agent-6
Product Specifications
UNSPSC Description
Antiproliferative agent-6 (compound 8a) is a potent antitumor agent. Antiproliferative agent-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antiproliferative-agent-6.html
Solubility
10 mM in DMSO
Smiles
N#CC1=C(C2=C(N3C1=NC4=C3C=CC=C4)C=C(C=C2)F)N5C=C(N=N5)CCCCl
Molecular Weight
404.83
References & Citations
[1]Meščić Macan A, et al. Synthesis, antiproliferative activity and DNA/RNA-binding properties of mono- and bis-(1,2,3-triazolyl)-appended benzimidazo[1,2-a]quinoline derivatives. Eur J Med Chem. 2020;185:111845.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146454/Antiproliferative-agent-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146454/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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