Anticancer agent 56
Product Specifications
UNSPSC Description
Anticancer agent 56 (compound 4d) is a potent anti-cancer agent with agent-likeness properties, possessing anticancer activity against several cancer cell lines (IC50apoptosis pathway. Anticancer agent 56 acts by accumulation of ROS, up regulation of BAX, down regulation of Bcl-2 and activation of caspases 3, 7, 9[1].
Target Antigen
Apoptosis; Bcl-2 Family; Caspase; Reactive Oxygen Species
Type
Reference compound
Related Pathways
Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-56.html
Solubility
10 mM in DMSO
Smiles
COC1=C(C=C(C=C1)/C=C/C(C2=C(N(N=N2)C3=CC=C(C=C3)Cl)C)=O)OC
Molecular Weight
383.83
References & Citations
[1]Ashour HF, et al. 1,2,3-Triazole-Chalcone hybrids: Synthesis, in vitro cytotoxic activity and mechanistic investigation of apoptosis induction in multiple myeloma RPMI-8226. Eur J Med Chem. 2020;189:112062.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146444/Anticancer-agent-56-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146444/
Clinical Information
No Development Reported
CAS Number
9007-83-4
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1193895-01 0.05 mg (E-Coli)
Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Protein tldD homolog (tldD)
Ask
View Details MBS1193895-02 0.05 mg (Yeast)
Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Protein tldD homolog (tldD)
Ask
View Details 
MBS1193895-03 0.05 mg (Baculovirus)
Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Protein tldD homolog (tldD)
Ask
View Details 
MBS1193895-04 0.2 mg (E-Coli)
Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Protein tldD homolog (tldD)
Ask
View Details MBS1193895-05 0.2 mg (Yeast)
Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Protein tldD homolog (tldD)
Ask
View Details MBS1193895-06 0.5 mg (E-Coli)
Recombinant Buchnera aphidicola subsp. Acyrthosiphon pisum Protein tldD homolog (tldD)
Ask
View Details