Prohibitin ligand 1
Prohibitin ligand 1 (Compound 22i), a cardioprotectant prohibitin ligand, induces a phosphorylation of the pro-survival factor STAT3. Prohibitin ligand 1 exhibits in vitro cardioprotectant activities at nanomolar concentrations[1].
Product Specifications
UNSPSC
12352005
Target
SPFH Protein Superfamily
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/prohibitin-ligand-1.html
Solubility
10 mM in DMSO
Smiles
CC(N1CC[C@]2([C@@H]1C3=CC=CC=C3)C(NC4=CC=CC=C42)=O)C
Molecular Formula
C20H22N2O
Molecular Weight
306.40
References & Citations
[1]Sabria Elderwish, et al. Discovery of 3,3'-pyrrolidinyl-spirooxindoles as cardioprotectant prohibitin ligands. Eur J Med Chem. 2020 Jan 15;186:111859.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Prohibitin
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