Topoisomerase I inhibitor 6
Product Specifications
UNSPSC Description
Topoisomerase I inhibitor 6 (Compound 3) is a potent inhibitor of Topoisomerase I. Topoisomerase I inhibitor 6 is able to trap DNA-Top1 cleavage complex and found to be less cytotoxic in non-cancerous cell line. Topoisomerase I inhibitor 6 has the potential for the research of cancer diseases[1].
Target Antigen
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-i-inhibitor-6.html
Solubility
10 mM in DMSO
Smiles
NC1=CC=C(C=C1)C2=CC=C3N=CC(C4=NN=CO4)=C(C3=C2)NCCCN5C=CN=C5
Molecular Weight
411.46
References & Citations
[1]Kundu B, et al. Development of a metabolically stable topoisomerase I poison as anticancer agent. Eur J Med Chem. 2020 Sep 15;202:112551. doi: 10.1016/j.ejmech.2020.112551.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146437/Topoisomerase-I-inhibitor-6-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146437/
Clinical Information
No Development Reported
CAS Number
2393082-56-7
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