Antiviral agent 20
Antiviral agent 20 (Compound 17b) is a selective inhibitor against Zika virus infection with an EC50 of 4.5 µM. Antiviral agent 20 has low cytotoxicity[1].
Product Specifications
CAS Number
[2407570-07-2]
UNSPSC
12352005
Target
Flavivirus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiviral-agent-20.html
Solubility
10 mM in DMSO
Smiles
[H][C@]12CCC([C@H]([C@@]1(CC[C@H]([C@]2(COC(C)=O)C)O)C)C/C=C3C(OC[C@H]/3OC4=C(C=C(C5=C4N=CC=C5)Cl)Cl)=O)=C
Molecular Formula
C31H35Cl2NO6
Molecular Weight
588.52
References & Citations
[1]Li F, et al. Design, synthesis and discovery of andrographolide derivatives against Zika virus infection. Eur J Med Chem. 2020 Feb 1;187:111925.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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