Anticancer agent 51

Anticancer agent 51 (compound 3d) is a potent anticancer agent with an Ki of 731.62 nM. Anticancer agent 51 shows anticancer activity. Anticancer agent 51 has the potential for the research of prostate cancer[1].

Product Specifications

CAS Number

2521777-38-6

UNSPSC

12352005

Target

MetAP

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-51.html

Solubility

10 mM in DMSO

Smiles

FC(F)(F)C(C=C1)=CC=C1NC(NNC([C@H](C2=CC3=C(C=C2)C=C(C=C3)OC)C)=O)=S

Molecular Formula

C22H20F3N3O2S

Molecular Weight

447.47

References & Citations

[1]Birgül K, et al. Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S) -naproxen derivatives. Eur J Med Chem. 2020 Dec 15;208:112841.