HCAI/II-IN-1
HCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor with IC50 values of 0.047 µM and 0.024 µM against hCA I and hCA II, respectively[1].
Product Specifications
CAS Number
2422028-82-6
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcai-ii-in-1.html
Solubility
10 mM in DMSO
Smiles
CN(CCCN1CCN(CC1)C(SCC(NC2=CC=C(C=C2)S(N)(=O)=O)=O)=S)C
Molecular Formula
C18H29N5O3S3
Molecular Weight
459.65
References & Citations
[1]Sağlık BN, et al. Synthesis, characterization and carbonic anhydrase I and II inhibitory evaluation of new sulfonamide derivatives bearing dithiocarbamate. Eur J Med Chem. 2020 Jul 15;198:112392.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA II; CA I
Frequently Asked Questions
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