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SARS-CoV-2-IN-19

SARS-CoV-2-IN-19 (Compound 6g) is a potent inhibitor of SARS-CoV-2 with an EC50 of 8.8 μM. SARS-CoV-2-IN-19 shows potent activity against SARS-CoV-2 helicase (nsp13), a highly conserved enzyme, highlighting a potentiality against emerging HCoVs outbreaks. SARS-CoV-2-IN-19 has the potential for the research of infection diseases[1].

Product Specifications

CAS Number

2244991-17-9

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-in-19.html

Solubility

10 mM in DMSO

Smiles

CCCOC1=CC=C(C=C1)C2=NC3=C(C(OCCN4CCC5=C(C4)C=C(C(OC)=C5)OC)=C2)C(OC)=CC(OC)=C3

Molecular Formula

C33H38N2O6

Molecular Weight

558.66

References & Citations

[1]Nizi MG, et al. Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity. ACS Med Chem Lett. 2022 May 3;13 (5) :855-864.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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