Tubulin polymerization-IN-20
Product Specifications
UNSPSC Description
Tubulin polymerization-IN-20 (compound 11) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-20.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(N2C([C@H]([C@@H]2C3=CC(F)=C(C=C3)OC)C4=CC=CC=C4)=O)=CC(OC)=C1OC
Molecular Weight
437.46
References & Citations
[1]Malebari AM, et al. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells. Eur J Med Chem. 2020;189:112050.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146378/Tubulin-polymerization-IN-20-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146378/
Clinical Information
No Development Reported
CAS Number
2410619-45-1
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