Tubulin polymerization-IN-20

Tubulin polymerization-IN-20 (compound 11) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-20 has the potential for the research of breast cancers and chemoresistant colon cancers[1].

Product Specifications

CAS Number

[2410619-45-1]

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tubulin-polymerization-in-20.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(N2C([C@H]([C@@H]2C3=CC(F)=C(C=C3)OC)C4=CC=CC=C4)=O)=CC(OC)=C1OC

Molecular Formula

C25H24FNO5

Molecular Weight

437.46

References & Citations

[1]Malebari AM, et al. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells. Eur J Med Chem. 2020;189:112050.