Tubulin polymerization-IN-18
Tubulin polymerization-IN-18 (compound 8) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-18 has the potential for the research of breast cancers and chemoresistant colon cancers[1].
Product Specifications
CAS Number
1258011-23-2
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-18.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(N2C([C@H]([C@@H]2C3=CC(O)=C(C=C3)OC)C4=CC=CC=C4)=O)=CC(OC)=C1OC
Molecular Formula
C25H25NO6
Molecular Weight
435.47
References & Citations
[1]Malebari AM, et al. β-Lactams with antiproliferative and antiapoptotic activity in breast and chemoresistant colon cancer cells. Eur J Med Chem. 2020;189:112050.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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