Antibacterial agent 95

The minimum inhibitory concentration (MIC) of a new 2- (quinoline-4-methoxy) acetamide antituberculotic agent against the reference strain of Mycobacterium tuberculosis H37Rv was as low as 0.3 μ M. It also inhibited the growth of Mycobacterium tuberculosis in the macrophage model of tuberculosis infection.

Product Specifications

CAS Number

[2413006-48-9]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-95.html

Solubility

10 mM in DMSO

Smiles

COC1=CC2=C(N=C(C=C2OCC(C3=CC=CC(Cl)=C3)=O)C)C=C1

Molecular Formula

C19H16ClNO3

Molecular Weight

341.79

References & Citations

[1]Borsoi AF, et al. Design, synthesis, and evaluation of new 2- (quinoline-4-yloxy) acetamide-based antituberculosis agents. Eur J Med Chem. 2020 Apr 15;192:112179.