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COX-2-IN-13

COX-2-IN-13 (compound 13e) is a potent and selective inhibitor of COX-2 with an IC50 of 0.98 μM. COX-2-IN-13 is an anti-inflammatory agent. COX-2-IN-13 shows safety in-vivo acute toxicity study[1].

Product Specifications

CAS Number

2987588-45-2

UNSPSC

12352005

Target

COX

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cox-2-in-13.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C=C1)C(CC2CC(N(C2=O)C3=CC=C(C=C3)S(N)(=O)=O)=O)=O

Molecular Formula

C19H18N2O5S

Molecular Weight

386.42

References & Citations

[1]Jan MS, et al. Design, synthesis, in-vitro, in-vivo and in-silico studies of pyrrolidine-2,5-dione derivatives as multitarget anti-inflammatory agents. Eur J Med Chem. 2020;186:111863.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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