CI-39
CI-39 is an antiviral natural product. CI-39 is an NNRTI (non-nucleoside reverse transcriptase inhibit) antiviral agent with an EC50 of 3.40 μM and an CC50 of >30 μM for wild type HIV-1. CI-39 inhibits HIV-1 RT DNA polymerase and ribonuclease H activitiessup[1].
Product Specifications
CAS Number
[2132412-25-8]
UNSPSC
12352005
Target
HIV
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ci-39.html
Solubility
10 mM in DMSO
Smiles
O=C(CC1=CN(C2=C1C=CC=C2)OC)NC3=C(C(OC)=O)C=CC=C3
Molecular Formula
C19H18N2O4
Molecular Weight
338.36
References & Citations
[1]Xu C, et al. Discovery, synthesis, and optimization of an N-alkoxy indolylacetamide against HIV-1 carrying NNRTI-resistant mutations from the Isatis indigotica root. Eur J Med Chem. 2020 Mar 1;189:112071.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HIV-1
Curated Selection
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