Tubulin polymerization-IN-17
Tubulin polymerization-IN-17 (compound 23g) is a potent inhibitor of tubulin polymerization. Tubulin polymerization-IN-17 exhibits tubulin depolymerization and induced cell apoptosis and inhibits migration. Tubulin polymerization-IN-17 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
2454175-89-2
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tubulin-polymerization-in-17.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(C(/C(C2=NC3=CC=CC=C3O2)=C/C4=CC=C(C=C4)C)=O)=CC(OC)=C1OC
Molecular Formula
C26H23NO5
Molecular Weight
429.46
References & Citations
[1]Guo Q, et al. Ligand- and structural-based discovery of potential small molecules that target the colchicine site of tubulin for cancer treatment. Eur J Med Chem. 2020;196:112328.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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