HIV-1 inhibitor-27
Product Specifications
UNSPSC Description
HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS[1].
Target Antigen
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-27.html
Solubility
10 mM in DMSO
Smiles
[H][C@@]12CC(C)(CC[C@@]1(CC[C@@]3([C@@]2(C(C[C@@]4([C@]5(CC[C@@H](C(C)([C@@]5(CC[C@]43C)[H])C)O)C)[H])=O)[H])C)C(NCCCCCCCC(N[C@H]([C@H](CC(O)=O)O)CC(C)C)=O)=O)C
Molecular Weight
771.12
References & Citations
[1]Takeuchi R, et al. Design, synthesis, and bio-evaluation of novel triterpenoid derivatives as anti-HIV-1 compounds. Bioorg Med Chem Lett. 2022;69:128768.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146339/HIV-1-inhibitor-27-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146339/
Clinical Information
No Development Reported
CAS Number
2302046-54-2
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