FtsZ-IN-2
FtsZ-IN-2 (Compound 19) is an inhibitor of the bacterial cell division protein FtsZ with GTPase inhibitory activity. FtsZ-IN-2 exhibits anti-staphylococcal activity with MIC values of 2 µg/ml for MSSA and MRSA[1].
Product Specifications
CAS Number
2249757-45-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ftsz-in-2.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(C=C1)CN2CCCN(CC2)CCC3=CC(C4=CC=CS4)=NC(C5=CC=NC=C5)=N3)C
Molecular Formula
C30H35N5S
Molecular Weight
497.70
References & Citations
[1]Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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