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FtsZ-IN-2

FtsZ-IN-2 (Compound 19) is an inhibitor of the bacterial cell division protein FtsZ with GTPase inhibitory activity. FtsZ-IN-2 exhibits anti-staphylococcal activity with MIC values of 2 µg/ml for MSSA and MRSA[1].

Product Specifications

CAS Number

2249757-45-5

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ftsz-in-2.html

Solubility

10 mM in DMSO

Smiles

CC(C1=CC=C(C=C1)CN2CCCN(CC2)CCC3=CC(C4=CC=CS4)=NC(C5=CC=NC=C5)=N3)C

Molecular Formula

C30H35N5S

Molecular Weight

497.70

References & Citations

[1]Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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