MIF-IN-5
MIF-IN-5 (compound 1d) is a potent and reversible macrophage migration inhibitory factor (MIF) competitive inhibitor with an IC50 of 4.8 μM and a Ki value of 3.3 μM, respectively[1].
Product Specifications
CAS Number
2582755-31-3
UNSPSC
12352005
Target
Macrophage migration inhibitory factor (MIF)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mif-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CN(N=N1)C2=CC(F)=C(C=C2)O)C3=CC4=CC=CC=C4N3
Molecular Formula
C18H14FN5O2
Molecular Weight
351.33
References & Citations
[1]Xiao Z, Fokkens M, Chen D, et al. Structure-activity relationships for binding of 4-substituted triazole-phenols to macrophage migration inhibitory factor (MIF) . Eur J Med Chem. 2020;186:111849.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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