Topoisomerase II inhibitor 6
Selected Variant
HY-146316
Size: 1 Each
Topoisomerase II inhibitor 6 (Compound 5), a tryptanthrin derivative, is a potent and selective inhibitor of topoisomerase II. Topoisomerase II inhibitor 6 exhibits antiproliferative activity on different tumor cell lines. Topoisomerase II inhibitor 6 blocks the cell cycle of CCRF-CEM in the G2 phase and induces DNA DSB. Topoisomerase II inhibitor 6 has the potential for the research of cancer diseases[1].
Product Specifications
CAS Number
2987586-62-7
UNSPSC
12352005
Target
Topoisomerase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/topoisomerase-ii-inhibitor-6.html
Solubility
10 mM in DMSO
Smiles
O=C1C2=NC3=C(C(N2C4=C1C(NCCN(C)C)=CC=C4)=O)C=CC=C3
Molecular Formula
C19H18N4O2
Molecular Weight
334.37
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Ep-CAM / CD326 (Extracellular Domain) (Epithelial Marker) (EGP40/1373), CF647 conjugate, 0.1mg/mL
PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL
Anti-CDCA5/Sororin Rabbit Monoclonal Antibody, Carrier-free
Anti-Intestinal FABP/FABP2 Antibody Picoband® (HRP Conjugate)
