AChE/BChE-IN-6
AChE/BChE-IN-6 (compound 22) is a potent dual AChE/BChE inhibitor with IC50 values of 0.809 μM, 2.248 μM and > 100 μM for hBChE, hAChE and hMAO-B, respectively. AChE/BChE-IN-6 penetrates the blood-brain barrier (BBB) . AChE/BChE-IN-6 can be used for Alzheimer’s disease (AD) research[1].
Product Specifications
CAS Number
2416910-94-4
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-6.html
Solubility
10 mM in DMSO
Smiles
CC(C1=CC=C(C=C1)NC(OCC2CCN(CC2)CC3=CC=CC=C3)=O)C
Molecular Formula
C23H30N2O2
Molecular Weight
366.50
References & Citations
[1]Košak U, et, al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; MAO-B
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