BChE-IN-7
BChE-IN-7 (compound 13) is a potent, selective, BBB-penetrated and reversible AChE and BChE inhibitor, with an IC50 of 0.06 μM (BChE) . BChE-IN-7 can protect neuronal-like cells from toxic Aβ-species[1].
Product Specifications
CAS Number
2416910-85-3
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-7.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1CCCN(C1)C2CC3=C(C2)C=CC=C3)NC4=CC=CC=C4
Molecular Formula
C21H24N2O2
Molecular Weight
336.43
References & Citations
[1]Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
BChE
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