INOS-IN-2

INOS-IN-2 (Compound 53) is a potent down-regulator of inducible nitric oxide synthase (iNOS) protein. iNOS-IN-2 effectively inhibits the NO production (IC50=6.4 μM) . iNOS-IN-2 has a potential therapeutic effect on chronic inflammation[1].

Product Specifications

CAS Number

2419891-42-0

UNSPSC

12352005

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/inos-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(OCCCN3CCOCC3)C(OC)=C2

Molecular Formula

C25H31NO7

Molecular Weight

457.52

References & Citations

[1]Youzhe Yang, et al. Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation. Eur J Med Chem. 2020 May 1;193:112216.