INOS-IN-2
INOS-IN-2 (Compound 53) is a potent down-regulator of inducible nitric oxide synthase (iNOS) protein. iNOS-IN-2 effectively inhibits the NO production (IC50=6.4 μM) . iNOS-IN-2 has a potential therapeutic effect on chronic inflammation[1].
Product Specifications
CAS Number
2419891-42-0
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/inos-in-2.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(OC)C=C(OC)C=C1O)/C=C/C2=CC=C(OCCCN3CCOCC3)C(OC)=C2
Molecular Formula
C25H31NO7
Molecular Weight
457.52
References & Citations
[1]Youzhe Yang, et al. Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation. Eur J Med Chem. 2020 May 1;193:112216.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS
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