YXL-13
YXL-13 is a potent Pseudomonas aeruginosa (PAO1) inhibitor with an IC50 value of 3.686 μM. YXL-13 can inhibit virulence factors and biofilm formation of PAO1. YXL-13 reduces the pathogenicity and agent resistance of PAO1 by inhibition of the quorum sensing (QS) system. YXL-13 can be used for researching anti-bacteria[1].
Product Specifications
CAS Number
2415981-79-0
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/yxl-13.html
Solubility
10 mM in DMSO
Smiles
O=C(NN1CCOC1=O)CCCOC2=CC=C(C=C2)Br
Molecular Formula
C13H15BrN2O4
Molecular Weight
343.17
References & Citations
[1]Jiang K, Yan X, Yu J, et al. Design, synthesis, and biological evaluation of 3-amino-2-oxazolidinone derivatives as potent quorum-sensing inhibitors of Pseudomonas aeruginosa PAO1. Eur J Med Chem. 2020;194:112252.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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