Xanthine oxidoreductase-IN-2

Xanthine oxidoreductase-IN-2 (Compound IVa) is a xanthine oxidoreductase (XOR) inhibitor with the IC50 of 7.2 nM. Xanthine oxidoreductase-IN-2 shows hypouricemic effects in mice[1].

Product Specifications

CAS Number

[2396612-45-4]

UNSPSC

12352005

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-oxidoreductase-in-2.html

Solubility

10 mM in DMSO

Smiles

CC(C)(C1=CC=C(C=C1)C2=C(C=C(C=C2)N3C=C(NC3)C(O)=O)C#N)C

Molecular Formula

C21H21N3O2

Molecular Weight

347.41

References & Citations

[1]Haiyan Zhou, et al. Synthesis and bioevaluation of 1-phenylimidazole-4-carboxylic acid derivatives as novel xanthine oxidoreductase inhibitors. Eur J Med Chem. 2020 Jan 15;186:111883.