Xanthine oxidoreductase-IN-2
Xanthine oxidoreductase-IN-2 (Compound IVa) is a xanthine oxidoreductase (XOR) inhibitor with the IC50 of 7.2 nM. Xanthine oxidoreductase-IN-2 shows hypouricemic effects in mice[1].
Product Specifications
CAS Number
[2396612-45-4]
UNSPSC
12352005
Target
Xanthine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidoreductase-in-2.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C1=CC=C(C=C1)C2=C(C=C(C=C2)N3C=C(NC3)C(O)=O)C#N)C
Molecular Formula
C21H21N3O2
Molecular Weight
347.41
References & Citations
[1]Haiyan Zhou, et al. Synthesis and bioevaluation of 1-phenylimidazole-4-carboxylic acid derivatives as novel xanthine oxidoreductase inhibitors. Eur J Med Chem. 2020 Jan 15;186:111883.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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