Xanthine oxidase-IN-7
Product Specifications
UNSPSC Description
Xanthine oxidase-IN-7 (compound1h) is a potent andorally active XO (xanthine oxidase) inhibitor with an IC50 of 0.36 µM. Xanthine oxidase-IN-7 effectively reduces serum uric acid levels. Xanthine oxidase-IN-7 has the potential for the research of hyperuricemia and gout[1].
Target Antigen
Xanthine Oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/xanthine-oxidase-in-7.html
Solubility
10 mM in DMSO
Smiles
N#CC1=CN(C2=CC=C(C=C12)C3=NOC(N3)=O)C4CCCC4
Molecular Weight
294.31
References & Citations
[1]Gao J, et al. Design, synthesis and biological evaluation of 1-alkyl-5/6-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)-1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors. Eur J Med Chem. 2020 Mar 15;190:112077.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146273/Xanthine-oxidase-IN-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146273/
Clinical Information
No Development Reported
CAS Number
2411698-59-2
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