Xanthine oxidase-IN-7

Xanthine oxidase-IN-7 (compound1h) is a potent andorally active XO (xanthine oxidase) inhibitor with an IC50 of 0.36 µM. Xanthine oxidase-IN-7 effectively reduces serum uric acid levels. Xanthine oxidase-IN-7 has the potential for the research of hyperuricemia and gout[1].

Product Specifications

CAS Number

[2411698-59-2]

UNSPSC

12352005

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-oxidase-in-7.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CN(C2=CC=C(C=C12)C3=NOC(N3)=O)C4CCCC4

Molecular Formula

C16H14N4O2

Molecular Weight

294.31

References & Citations

[1]Gao J, et al. Design, synthesis and biological evaluation of 1-alkyl-5/6- (5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl) -1H-indole-3-carbonitriles as novel xanthine oxidase inhibitors. Eur J Med Chem. 2020 Mar 15;190:112077.