PUL89 Endonuclease-IN-2
PUL89 Endonuclease-IN-2 (Compound 15k) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 of 3.0 μM. Antiviral activities[1].
Product Specifications
CAS Number
519021-48-8
UNSPSC
12352005
Target
CMV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/pul89-endonuclease-in-2.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C(NCC2=CC=C(C(F)(F)F)C=C2)=O)N=C(C3=CC=CS3)N=C1O
Molecular Formula
C17H12F3N3O3S
Molecular Weight
395.36
References & Citations
[1]Tianyu He, et al. 4,5-Dihydroxypyrimidine Methyl Carboxylates, Carboxylic Acids, and Carboxamides as Inhibitors of Human Cytomegalovirus pUL89 Endonuclease. J Med Chem. 2022 Apr 14;65 (7) :5830-5849.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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