hCAXII-IN-5
Product Specifications
UNSPSC Description
hCAXII-IN-5 (compound 6o) is a potent and selective hCAXII inhibitor with Ki values of >10000, >10000, 286.1, 1.0 nM for hCAI, hCAII, hCAIX and hCAXII, respectively[1].
Target Antigen
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaxii-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C)C2=C(O1)C=C(OCC3=NOC(C4=CC=C(C(C)(C)C)C=C4)=N3)C=C2
Molecular Weight
390.43
References & Citations
[1]Thacker PS, et al. Design, synthesis and biological evaluation of coumarin linked 1,2,4-oxadiazoles as selective carbonic anhydrase IX and XII inhibitors. Bioorg Chem. 2020 May;98:103739.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-146256/hCAXII-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-146256/
Clinical Information
No Development Reported
CAS Number
2414629-92-6
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