Antitumor agent-71
Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.
Product Specifications
CAS Number
2011756-99-1
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitumor-agent-71.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC2=C(C=C1)N(C)C3=C2C=C(CN4CCN(C)CC4)C=C3)(NC5=CC=C(OC)N=C5OC)=O
Molecular Formula
C26H31N5O4S
Molecular Weight
509.62
References & Citations
[1]Lianqi Sun, et al. Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents. Bioorg Chem. 2020 Jun;99:103766.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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