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Antitumor agent-71

Antitumor Agent-71 is an antiproliferative activity antitumor agent and against tumor cell lines with IC50 values ranging from 3.98-15.70 μM. Antitumor Agent-71 is an antitumor agent that can inhibit tubulin polymerization.

Product Specifications

CAS Number

2011756-99-1

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-71.html

Solubility

10 mM in DMSO

Smiles

O=S(C1=CC2=C(C=C1)N(C)C3=C2C=C(CN4CCN(C)CC4)C=C3)(NC5=CC=C(OC)N=C5OC)=O

Molecular Formula

C26H31N5O4S

Molecular Weight

509.62

References & Citations

[1]Lianqi Sun, et al. Design, synthesis, and evaluations of the antiproliferative activity and aqueous solubility of novel carbazole sulfonamide derivatives as antitumor agents. Bioorg Chem. 2020 Jun;99:103766.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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