F 13714
F 13714 (F 14679) is a prototypical 5-HT1A agonist with a pKi of 10.23. F 13714 induces large Ca2+ responses[1].
Product Specifications
CAS Number
208109-38-0
Product Name Alternative
F 14679
UNSPSC
12352005
Hazard Statement
H315-H319
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/f-13714.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC(Cl)=C(F)C=C1)N2CCC(CNCC3=CC=C(C)C(NC)=N3)(F)CC2
Molecular Formula
C21H25ClF2N4O
Molecular Weight
422.90
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Pauwels PJ, et al. Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation. J Pharmacol Exp Ther. 2003 Nov;307 (2) :608-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT1 Receptor; mLAG-3
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