COX-2-IN-19
COX-2-IN-19 (Compound 24) is a potent COX-2 inhibitor with an IC50 of 1.76 μM. COX-2-IN-19 shows in vivo anti-inflammatory activity[1].
Product Specifications
CAS Number
[2497530-12-6]
UNSPSC
12352005
Target
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cox-2-in-19.html
Solubility
10 mM in DMSO
Smiles
S=C1NN=C(CC2=CC=C(C)C=C2)N1/N=C/C3=CC=C(OC)C=C3O
Molecular Formula
C18H18N4O2S
Molecular Weight
354.43
References & Citations
[1]Munir A, et al. Synthesis, in-vitro, in-vivo anti-inflammatory activities and molecular docking studies of acyl and salicylic acid hydrazide derivatives. Bioorg Chem. 2020 Nov;104:104168.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
COX-1; COX-2
Curated Selection
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